On September 24, 2010, a six-alarm fire broke out at 200 Wellesley Street East, a 711-unit Toronto Community Housing high-rise, displacing approximately 1,200 residents and injuring multiple people. Canadian Medical Assistance Teams (CMAT) activated a domestic relief effort to support displaced households during the early recovery phase. In coordination with municipal and community partners, CMAT procured and distributed clean‑up and recovery kits to affected households and ran a targeted donations appeal to fund essential items for evacuees.

The fire originated on the 24th‑floor balcony of unit 2424 and escalated rapidly due to combustible materials, with the Ontario Fire Marshal later identifying a discarded cigarette butt as the ignition source. Seventeen people, including five children and three firefighters, were reported injured. Hundreds of evacuees were accommodated in community centres while structural assessments and phased re‑entry were conducted.

In late September to early October 2010, the Canadian Medical Assistance Teams (CMAT) activated in response to a fire, aligning its timeline with the municipal response and resident re-entry phases. The mission aimed to rapidly identify non-food item (NFI) needs for displaced households, procure and distribute household clean-up and recovery kits to reduce post-fire health risks such as exposure to smoke and soot particulates, and complement rather than duplicate the work of municipal authorities and the Canadian Red Cross. A volunteer team purchased, assembled, and delivered clean-up kits sourced from Home Depot, distributing 40 kits in the first tranche to support safe cleaning and re-occupation of smoke- and soot-damaged dwellings, while a targeted donations appeal raised funds for essential items — diapers, toiletries, and underwear — for evacuees registered at local reception centres, based on needs flagged by community partners. Throughout, CMAT designed its activities to complement the City of Toronto, Toronto Community Housing, and Canadian Red Cross operations at reception centres, avoiding duplication and focusing on immediate household recovery, with public updates from Toronto Community Housing guiding the timing of support and phased re-entry.